Topical folinic acid enhances wound healing in rat model
Articles > Article ยท 2018
Authors: Nilay DUMAN, Resat Duman, Murat Tosun, Murat Akici, Engin Goksel, Baris Gokce, Oguzhan Alagoz
ADVANCES IN MEDICAL SCIENCES, Journal Indexed in SCI Expanded, International, 2018, vol 63, pp 347-352
DOI: 10.1016/j.advms.2018.04.011
Summary
Purpose: Folic acid is an essential vitamin participating in DNA synthesis and repair. Recently folic acid has been shown to stimulate DNA-repair capacity in dermal fibroblasts in response to injury. Thus, the present study aimed to investigate the effects of topical folinic acid, a 5-formyl derivative of tetrahydrofolic acid, on wound healing using rat wound model.