Topical folinic acid enhances wound healing in rat model
Makaleler > Tam Makale · 2018
Yazarlar: Nilay DUMAN, Resat Duman, Murat Tosun, Murat Akici, Engin Goksel, Baris Gokce, Oguzhan Alagoz
ADVANCES IN MEDICAL SCIENCES, SCI Expanded İndekslerine Giren Dergi, Uluslararası, 2018, cilt 63, ss 347-352
DOI: 10.1016/j.advms.2018.04.011
Özet
Purpose: Folic acid is an essential vitamin participating in DNA synthesis and repair. Recently folic acid has been shown to stimulate DNA-repair capacity in dermal fibroblasts in response to injury. Thus, the present study aimed to investigate the effects of topical folinic acid, a 5-formyl derivative of tetrahydrofolic acid, on wound healing using rat wound model.