MİKROBİYOTA İÇİMİZDEKİ EVREN
Kitaplar > Mesleki Kitap · 2020
Yazarlar: Özlem YILMAZ
Mesleki Kitap, 2020, Ege Üniversitesi, Üniversite, Türkiye, İzmir, Ulusal
Özet
<p><span style="left: 94.463px; top: 144.845px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.01122);">Son y</span><span style="left: 139.818px; top: 144.845px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 143.988px; top: 144.845px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.03023);">llarda mikrobiyotan</span><span style="left: 276.813px; top: 144.845px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 280.817px; top: 144.845px; font-size: 14.9983px; font-family: sans-serif;">n</span><span style="left: 300.516px; top: 144.845px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(0.998603);">insan sa</span><span style="left: 363.404px; top: 144.845px; font-size: 14.9983px; font-family: sans-serif;">ğ</span><span style="left: 371.608px; top: 144.845px; font-size: 14.9983px; font-family: sans-serif;">l</span><span style="left: 374.998px; top: 144.845px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 379.167px; top: 144.845px; font-size: 14.9983px; font-family: sans-serif;">ğ</span><span style="left: 387.581px; top: 144.845px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 391.586px; top: 144.845px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.0107);">ndaki önemine </span><span style="left: 94.4615px; top: 164.843px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.12887);">ili</span><span style="left: 104.435px; top: 164.843px; font-size: 14.9983px; font-family: sans-serif;">ş</span><span style="left: 112.025px; top: 164.843px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.06556);">kin çok say</span><span style="left: 197.095px; top: 164.843px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 201.265px; top: 164.843px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.06978);">da ara</span><span style="left: 249.409px; top: 164.843px; font-size: 14.9983px; font-family: sans-serif;">ş</span><span style="left: 256.803px; top: 164.843px; font-size: 14.9983px; font-family: sans-serif;">t</span><span style="left: 260.973px; top: 164.843px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 265.188px; top: 164.843px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.04381);">rma yap</span><span style="left: 324.731px; top: 164.843px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 328.9px; top: 164.843px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(0.975454);">lm</span><span style="left: 344.709px; top: 164.843px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 348.878px; top: 164.843px; font-size: 14.9983px; font-family: sans-serif;">ş</span><span style="left: 356.302px; top: 164.843px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.07181);"> ve mikrobiyotadaki </span><span style="left: 94.4615px; top: 184.842px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.07484);">kalitatif ve kantitatif de</span><span style="left: 257.658px; top: 184.842px; font-size: 14.9983px; font-family: sans-serif;">ğ</span><span style="left: 266.042px; top: 184.842px; font-size: 14.9983px; font-family: sans-serif;">i</span><span style="left: 269.432px; top: 184.842px; font-size: 14.9983px; font-family: sans-serif;">ş</span><span style="left: 276.826px; top: 184.842px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.05536);">ikliklerin sadece ba</span><span style="left: 413.866px; top: 184.842px; font-size: 14.9983px; font-family: sans-serif;">ğ</span><span style="left: 422.25px; top: 184.842px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 426.42px; top: 184.842px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.04585);">rsak de</span><span style="left: 480.804px; top: 184.842px; font-size: 14.9983px; font-family: sans-serif;">ğ</span><span style="left: 489.188px; top: 184.842px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.04148);">il </span><span style="left: 94.46px; top: 204.84px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.04782);">ba</span><span style="left: 111.228px; top: 204.84px; font-size: 14.9983px; font-family: sans-serif;">ğ</span><span style="left: 119.612px; top: 204.84px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 123.782px; top: 204.84px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(0.994921);">rsak d</span><span style="left: 171.746px; top: 204.84px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 175.916px; top: 204.84px; font-size: 14.9983px; font-family: sans-serif;">ş</span><span style="left: 183.535px; top: 204.84px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 187.705px; top: 204.84px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.01292);"> birçok kronik hastal</span><span style="left: 341.753px; top: 204.84px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 345.922px; top: 204.84px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.02018);">kla da ili</span><span style="left: 414.449px; top: 204.84px; font-size: 14.9983px; font-family: sans-serif;">ş</span><span style="left: 421.844px; top: 204.84px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.0384);">kili oldu</span><span style="left: 479.152px; top: 204.84px; font-size: 14.9983px; font-family: sans-serif;">ğ</span><span style="left: 487.356px; top: 204.84px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.01939);">u </span><span style="left: 94.46px; top: 224.839px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.02024);">gösterilmi</span><span style="left: 158.563px; top: 224.839px; font-size: 14.9983px; font-family: sans-serif;">ş</span><span style="left: 166.152px; top: 224.839px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.06561);">tir. Otoimmün, alerjik ve kronik inflama</span><span style="left: 470.546px; top: 224.839px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.02692);">tuar </span><span style="left: 94.46px; top: 244.836px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.029);">hastal</span><span style="left: 134.596px; top: 244.836px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 138.6px; top: 244.836px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.02331);">klardaki rolünü ortaya koyan giderek artan say</span><span style="left: 463.929px; top: 244.836px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 468.098px; top: 244.836px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.05363);">daki </span><span style="left: 94.4585px; top: 264.885px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.03524);">ara</span><span style="left: 116.221px; top: 264.885px; font-size: 14.9983px; font-family: sans-serif;">ş</span><span style="left: 123.81px; top: 264.885px; font-size: 14.9983px; font-family: sans-serif;">t</span><span style="left: 127.98px; top: 264.885px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 132.194px; top: 264.885px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.05832);">rmayla da mikrobiyotan</span><span style="left: 299.381px; top: 264.885px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 303.55px; top: 264.885px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.08771);">n sa</span><span style="left: 338.316px; top: 264.885px; font-size: 14.9983px; font-family: sans-serif;">ğ</span><span style="left: 346.521px; top: 264.885px; font-size: 14.9983px; font-family: sans-serif;">l</span><span style="left: 349.91px; top: 264.885px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 354.08px; top: 264.885px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.0844);">ktaki önemi giderek </span><span style="left: 94.4585px; top: 284.883px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.04353);">daha ön plana ç</span><span style="left: 227.045px; top: 284.883px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 231.215px; top: 284.883px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.02938);">kmaktad</span><span style="left: 287.804px; top: 284.883px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 291.973px; top: 284.883px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.05241);">r. Ba</span><span style="left: 332.169px; top: 284.883px; font-size: 14.9983px; font-family: sans-serif;">ğ</span><span style="left: 340.553px; top: 284.883px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 344.722px; top: 284.883px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.02817);">rsak mikrobiyomunun </span><span style="left: 94.4585px; top: 304.881px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.04782);">ba</span><span style="left: 111.227px; top: 304.881px; font-size: 14.9983px; font-family: sans-serif;">ğ</span><span style="left: 119.611px; top: 304.881px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 123.615px; top: 304.881px; font-size: 14.9983px; font-family: sans-serif;">ş</span><span style="left: 131.204px; top: 304.881px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 135.374px; top: 304.881px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.06788);">kl</span><span style="left: 146.188px; top: 304.881px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 150.357px; top: 304.881px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.05688);">k sisteminin olu</span><span style="left: 264.45px; top: 304.881px; font-size: 14.9983px; font-family: sans-serif;">ş</span><span style="left: 271.844px; top: 304.881px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.02341);">umunu </span><span style="left: 327.563px; top: 304.881px; font-size: 14.9983px; font-family: sans-serif;">ş</span><span style="left: 335.152px; top: 304.881px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.05594);">ekillendirerek sa</span><span style="left: 449.199px; top: 304.881px; font-size: 14.9983px; font-family: sans-serif;">ğ</span><span style="left: 457.583px; top: 304.881px; font-size: 14.9983px; font-family: sans-serif;">l</span><span style="left: 460.973px; top: 304.881px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 464.977px; top: 304.881px; font-size: 14.9983px; font-family: sans-serif;">ğ</span><span style="left: 473.361px; top: 304.881px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.14121);">a / </span><span style="left: 94.4585px; top: 324.879px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.029);">hastal</span><span style="left: 134.594px; top: 324.879px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 138.768px; top: 324.876px; font-size: 14.9983px; font-family: sans-serif;">ğ</span><span style="left: 147.002px; top: 324.876px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.08024);">a katk</span><span style="left: 187.947px; top: 324.876px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 192.117px; top: 324.876px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.05812);">da bulundu</span><span style="left: 267.243px; top: 324.876px; font-size: 14.9983px; font-family: sans-serif;">ğ</span><span style="left: 275.627px; top: 324.876px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.04743);">unu gösteren çal</span><span style="left: 388.767px; top: 324.876px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 392.772px; top: 324.876px; font-size: 14.9983px; font-family: sans-serif;">ş</span><span style="left: 400.166px; top: 324.876px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.05016);">malar özellikle </span><span style="left: 94.4624px; top: 344.875px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.03572);">intestinal sistem mikrobiyotas</span><span style="left: 292.229px; top: 344.875px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 296.234px; top: 344.875px; font-size: 14.9983px; font-family: sans-serif;">n</span><span style="left: 304.618px; top: 344.875px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 308.787px; top: 344.875px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(0.95621);"> ilgi oda</span><span style="left: 363.111px; top: 344.875px; font-size: 14.9983px; font-family: sans-serif;">ğ</span><span style="left: 371.495px; top: 344.875px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 375.665px; top: 344.875px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(0.98057);"> haline getirmi</span><span style="left: 471.534px; top: 344.875px; font-size: 14.9983px; font-family: sans-serif;">ş</span><span style="left: 479.123px; top: 344.875px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.08256);">tir. </span><span style="left: 94.4624px; top: 364.872px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.03697);">Mikrobiyota arac</span><span style="left: 211.704px; top: 364.872px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 215.874px; top: 364.872px; font-size: 14.9983px; font-family: sans-serif;">l</span><span style="left: 219.294px; top: 364.872px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 223.298px; top: 364.872px; font-size: 14.9983px; font-family: sans-serif;">ğ</span><span style="left: 231.682px; top: 364.872px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 235.852px; top: 364.872px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.00665);"> ile tedavi sa</span><span style="left: 340.735px; top: 364.872px; font-size: 14.9983px; font-family: sans-serif;">ğ</span><span style="left: 348.939px; top: 364.872px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.00063);">lamak amac</span><span style="left: 437.039px; top: 364.872px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 441.209px; top: 364.872px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(0.996753);">yla son </span><span style="left: 94.4624px; top: 384.871px; font-size: 14.9983px; font-family: sans-serif;">y</span><span style="left: 101.857px; top: 384.871px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 106.026px; top: 384.871px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.01744);">llarda yeni bir kavram olan “mikrobiyota manipülasyonu” </span><span style="left: 94.4624px; top: 404.87px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.03899);">ortaya at</span><span style="left: 177.373px; top: 404.87px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 181.543px; top: 404.87px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(0.999826);">lm</span><span style="left: 197.366px; top: 404.87px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 201.536px; top: 404.87px; font-size: 14.9983px; font-family: sans-serif;">ş</span><span style="left: 209.155px; top: 404.87px; font-size: 14.9983px; font-family: sans-serif;">t</span><span style="left: 213.324px; top: 404.87px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 217.539px; top: 404.87px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.05049);">r. Probiyotikler, prebiyotikl</span><span style="left: 438.551px; top: 404.87px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.02792);">er ve </span><span style="left: 94.4624px; top: 424.869px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.04484);">antibiyotiklerin kullan</span><span style="left: 248.045px; top: 424.869px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 252.05px; top: 424.869px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(0.99139);">lmas</span><span style="left: 283.816px; top: 424.869px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 287.986px; top: 424.869px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.01579);">, bunun yan</span><span style="left: 396.499px; top: 424.869px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 420.352px; top: 424.869px; font-size: 14.9983px; font-family: sans-serif;">s</span><span style="left: 427.941px; top: 424.869px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 432.111px; top: 424.869px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.00449);">ra fekal </span><span style="left: 94.4609px; top: 444.899px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.01377);">mikrobiyota tranplantasyonu yöntemi, bu konuda kullan</span><span style="left: 471.534px; top: 444.899px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 475.704px; top: 444.899px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.03704);">lan </span><span style="left: 94.4609px; top: 464.898px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.04782);">ba</span><span style="left: 111.229px; top: 464.898px; font-size: 14.9983px; font-family: sans-serif;">ş</span><span style="left: 118.818px; top: 464.898px; font-size: 14.9983px; font-family: sans-serif;">l</span><span style="left: 122.013px; top: 464.898px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 126.182px; top: 464.898px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.02918);">ca yakla</span><span style="left: 188.935px; top: 464.898px; font-size: 14.9983px; font-family: sans-serif;">ş</span><span style="left: 196.525px; top: 464.898px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 200.694px; top: 464.898px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.0041);">mlar aras</span><span style="left: 271.051px; top: 464.898px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 275.221px; top: 464.898px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.04356);">ndad</span><span style="left: 308.607px; top: 464.898px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 312.777px; top: 464.898px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.06487);">r. Mikrobiyotay</span><span style="left: 418.05px; top: 464.898px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 422.22px; top: 464.898px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.0314);"> olu</span><span style="left: 454.196px; top: 464.898px; font-size: 14.9983px; font-family: sans-serif;">ş</span><span style="left: 461.785px; top: 464.898px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.02248);">turan </span><span style="left: 94.4609px; top: 484.897px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.02063);">mikroorganizmalar</span><span style="left: 217.897px; top: 484.897px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 221.902px; top: 484.897px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.04369);">n türü ve yo</span><span style="left: 325.375px; top: 484.897px; font-size: 14.9983px; font-family: sans-serif;">ğ</span><span style="left: 333.759px; top: 484.897px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.05516);">unluklar</span><span style="left: 386.479px; top: 484.897px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 390.483px; top: 484.897px; font-size: 14.9983px; font-family: sans-serif;">n</span><span style="left: 398.867px; top: 484.897px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 403.037px; top: 484.897px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.02566);">n, sa</span><span style="left: 444.012px; top: 484.897px; font-size: 14.9983px; font-family: sans-serif;">ğ</span><span style="left: 452.216px; top: 484.897px; font-size: 14.9983px; font-family: sans-serif;">l</span><span style="left: 455.606px; top: 484.897px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 459.775px; top: 484.897px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.0519);">k ve </span><span style="left: 94.4609px; top: 504.894px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.029);">hastal</span><span style="left: 134.596px; top: 504.894px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 138.601px; top: 504.894px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.03212);">klardaki önemi ön plana ç</span><span style="left: 324.457px; top: 504.894px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 328.462px; top: 504.894px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.03265);">kmaktad</span><span style="left: 385.216px; top: 504.894px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 389.385px; top: 504.894px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.06991);">r. Ayr</span><span style="left: 428.966px; top: 504.894px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 433.135px; top: 504.894px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.00777);">ca içeri</span><span style="left: 484.475px; top: 504.894px; font-size: 14.9983px; font-family: sans-serif;">ğ</span><span style="left: 492.679px; top: 504.894px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.03189);">i </span><span style="left: 94.4609px; top: 524.893px; font-size: 14.9983px; font-family: sans-serif;">d</span><span style="left: 102.845px; top: 524.893px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 107.015px; top: 524.893px; font-size: 14.9983px; font-family: sans-serif;">ş</span><span style="left: 114.634px; top: 524.893px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 118.803px; top: 524.893px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.03569);">nda, mikrobiyotan</span><span style="left: 249.304px; top: 524.893px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 253.475px; top: 524.889px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.03696);">n metabolik i</span><span style="left: 362.168px; top: 524.889px; font-size: 14.9983px; font-family: sans-serif;">ş</span><span style="left: 369.757px; top: 524.889px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.03044);">levleri de önem </span><span style="left: 94.4625px; top: 544.887px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.01282);">kazanm</span><span style="left: 147.002px; top: 544.887px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 151.171px; top: 544.887px; font-size: 14.9983px; font-family: sans-serif;">ş</span><span style="left: 158.79px; top: 544.887px; font-size: 14.9983px; font-family: sans-serif;">t</span><span style="left: 162.96px; top: 544.887px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 167.174px; top: 544.887px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.04435);">r. Son y</span><span style="left: 234.922px; top: 544.887px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 239.091px; top: 544.887px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.03823);">llarda Metabolomik (salg</span><span style="left: 417.662px; top: 544.887px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 421.831px; top: 544.887px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.02592);">lanan tüm </span><span style="left: 94.4625px; top: 564.885px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.04565);">metabolitlerin ayr</span><span style="left: 213.684px; top: 564.885px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 217.854px; top: 564.885px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.02439);">nt</span><span style="left: 230.257px; top: 564.885px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 234.472px; top: 564.885px; font-size: 14.9983px; font-family: sans-serif;">l</span><span style="left: 237.862px; top: 564.885px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 241.866px; top: 564.885px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.05154);"> ve kantitatif ölçümü) ve Proteomik </span><span style="left: 94.4625px; top: 584.883px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.05041);">(proteinlerin yap</span><span style="left: 202.675px; top: 584.883px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 206.845px; top: 584.883px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.10024);"> ve i</span><span style="left: 235.612px; top: 584.883px; font-size: 14.9983px; font-family: sans-serif;">ş</span><span style="left: 243.201px; top: 584.883px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.05408);">levlerinin ayr</span><span style="left: 327.672px; top: 584.883px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 331.841px; top: 584.883px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.05463);">nt</span><span style="left: 344.425px; top: 584.883px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 348.639px; top: 584.883px; font-size: 14.9983px; font-family: sans-serif;">l</span><span style="left: 352.029px; top: 584.883px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 356.198px; top: 584.883px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.07031);"> ve kantitatif</span><span style="left: 442.949px; top: 584.883px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.00649);">ölçümü) </span><span style="left: 94.461px; top: 604.882px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.04969);">yöntemleri ile çe</span><span style="left: 221.272px; top: 604.882px; font-size: 14.9983px; font-family: sans-serif;">ş</span><span style="left: 228.861px; top: 604.882px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.05785);">itli hastal</span><span style="left: 296.369px; top: 604.882px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 300.538px; top: 604.882px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.06119);">klarda de</span><span style="left: 371.645px; top: 604.882px; font-size: 14.9983px; font-family: sans-serif;">ğ</span><span style="left: 379.849px; top: 604.882px; font-size: 14.9983px; font-family: sans-serif;">i</span><span style="left: 383.239px; top: 604.882px; font-size: 14.9983px; font-family: sans-serif;">ş</span><span style="left: 390.633px; top: 604.882px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.0557);">en fonksiyonel </span><span style="left: 94.461px; top: 624.929px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.03536);">mikrobiyota örüntüleri ara</span><span style="left: 279.765px; top: 624.929px; font-size: 14.9983px; font-family: sans-serif;">ş</span><span style="left: 287.355px; top: 624.929px; font-size: 14.9983px; font-family: sans-serif;">t</span><span style="left: 291.359px; top: 624.929px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 295.364px; top: 624.929px; font-size: 14.9983px; font-family: sans-serif;">r</span><span style="left: 300.358px; top: 624.929px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 304.528px; top: 624.929px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.0318);">lmaktad</span><span style="left: 357.112px; top: 624.929px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 361.281px; top: 624.929px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.04478);">r. Çal</span><span style="left: 405.256px; top: 624.929px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 409.261px; top: 624.929px; font-size: 14.9983px; font-family: sans-serif;">ş</span><span style="left: 416.85px; top: 624.929px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.01045);">malar hem </span><span style="left: 94.461px; top: 644.928px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.02063);">mikroorganizmalar</span><span style="left: 217.897px; top: 644.928px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 221.902px; top: 644.928px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.08385);">n hem de kona</span><span style="left: 338.964px; top: 644.928px; font-size: 14.9983px; font-family: sans-serif;">ğ</span><span style="left: 347.348px; top: 644.928px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 351.517px; top: 644.928px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.07151);">n mutualistik ili</span><span style="left: 460.825px; top: 644.928px; font-size: 14.9983px; font-family: sans-serif;">ş</span><span style="left: 468.219px; top: 644.928px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.05308);">kiler </span><span style="left: 94.461px; top: 664.927px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.06952);">geli</span><span style="left: 117.813px; top: 664.927px; font-size: 14.9983px; font-family: sans-serif;">ş</span><span style="left: 125.403px; top: 664.927px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.01149);">tirerek birbirlerine ba</span><span style="left: 266.222px; top: 664.927px; font-size: 14.9983px; font-family: sans-serif;">ğ</span><span style="left: 274.606px; top: 664.927px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 278.611px; top: 664.927px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.0002);">ml</span><span style="left: 294.584px; top: 664.927px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 298.588px; top: 664.927px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.01629);"> olduklar</span><span style="left: 357.502px; top: 664.927px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 361.671px; top: 664.927px; font-size: 14.9983px; font-family: sans-serif;">n</span><span style="left: 370.085px; top: 664.927px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 374.09px; top: 664.927px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(0.983625);"> ve mikrobiyomun </span><span style="left: 94.461px; top: 684.925px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.00447);">bozulmas</span><span style="left: 158.774px; top: 684.925px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 162.943px; top: 684.925px; font-size: 14.9983px; font-family: sans-serif;">n</span><span style="left: 171.177px; top: 684.925px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 175.347px; top: 684.925px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.01267);">n; her olguda nedensellik ili</span><span style="left: 366.61px; top: 684.925px; font-size: 14.9983px; font-family: sans-serif;">ş</span><span style="left: 374.199px; top: 684.925px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(0.992413);">kisi gösterilemese </span><span style="left: 94.461px; top: 704.923px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.05651);">de kronik hastal</span><span style="left: 218.107px; top: 704.923px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 222.277px; top: 704.923px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.04547);">klar, otoimmün hastal</span><span style="left: 383.299px; top: 704.923px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 387.303px; top: 704.923px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.05231);">klar ve artm</span><span style="left: 484.193px; top: 704.923px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 488.197px; top: 704.923px; font-size: 14.9983px; font-family: sans-serif;">ş</span><span style="left: 94.461px; top: 724.921px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.03209);">infeksiyon riski gibi çok say</span><span style="left: 290.399px; top: 724.921px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 294.569px; top: 724.921px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.03391);">da hastal</span><span style="left: 359.512px; top: 724.921px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 363.681px; top: 724.921px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.06805);">kla ili</span><span style="left: 401.042px; top: 724.921px; font-size: 14.9983px; font-family: sans-serif;">ş</span><span style="left: 408.436px; top: 724.921px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.06035);">kili oldu</span><span style="left: 462.535px; top: 724.921px; font-size: 14.9983px; font-family: sans-serif;">ğ</span><span style="left: 470.739px; top: 724.921px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.03558);">unu </span><span style="left: 94.461px; top: 744.913px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.05148);">ortaya koymaktad</span><span style="left: 222.892px; top: 744.913px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 227.061px; top: 744.913px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.08462);">r. Tüm bu geli</span><span style="left: 348.355px; top: 744.909px; font-size: 14.9983px; font-family: sans-serif;">ş</span><span style="left: 355.944px; top: 744.909px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.05959);">meler göz önünde </span><span style="left: 94.4632px; top: 764.906px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.0464);">bulunduruldu</span><span style="left: 181.154px; top: 764.906px; font-size: 14.9983px; font-family: sans-serif;">ğ</span><span style="left: 189.538px; top: 764.906px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.02339);">unda, ki</span><span style="left: 256.865px; top: 764.906px; font-size: 14.9983px; font-family: sans-serif;">ş</span><span style="left: 264.454px; top: 764.906px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.00138);">iye özel t</span><span style="left: 353.364px; top: 764.906px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 357.534px; top: 764.906px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.02472);">p uygulamalar</span><span style="left: 467.142px; top: 764.906px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 471.311px; top: 764.906px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.03783);">nda </span><span style="left: 94.4617px; top: 784.905px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.0379);">mikrobiyotan</span><span style="left: 179.532px; top: 784.905px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 183.702px; top: 784.905px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.01582);">n gelecekte çok önemli bir hedef olaca</span><span style="left: 483.174px; top: 784.905px; font-size: 14.9983px; font-family: sans-serif;">ğ</span><span style="left: 491.558px; top: 784.905px; font-size: 14.9983px; font-family: monospace;">ı </span><span style="left: 94.462px; top: 98.0506px; font-size: 14.9983px; font-family: sans-serif;">a</span><span style="left: 102.846px; top: 98.0506px; font-size: 14.9983px; font-family: sans-serif;">ş</span><span style="left: 110.435px; top: 98.0506px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.04384);">ikârd</span><span style="left: 142.982px; top: 98.0506px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 147.151px; top: 98.0506px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.07567);">r. Bu kitapta mikrobiyota konusu ile ilgili güncel </span><span style="left: 94.462px; top: 117.848px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.05307);">bilgiler farkl</span><span style="left: 170.369px; top: 117.848px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 174.538px; top: 117.848px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.05332);"> yönleriyle ele al</span><span style="left: 281.986px; top: 117.848px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 286.156px; top: 117.848px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(0.981748);">nm</span><span style="left: 306.973px; top: 117.848px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 311.143px; top: 117.848px; font-size: 14.9983px; font-family: sans-serif;">ş</span><span style="left: 318.762px; top: 117.848px; font-size: 14.9983px; font-family: sans-serif;">t</span><span style="left: 322.932px; top: 117.848px; font-size: 14.9983px; font-family: monospace;">ı</span><span style="left: 326.966px; top: 117.848px; font-size: 14.9983px; font-family: sans-serif; transform: scaleX(1.1115);">r.</span><br></p>