Design of Carbon Nanotube Modified Conducting Polymer for Biosensing Applications
Articles > Article · 2011
Authors: Caglar OZDEMIR, Sevinc Tuncagil, Dilek ODACI, Suna TİMUR, Levent Toppare
Journal of Macromolecular Science, Part A, Journal Indexed in SCI Expanded, International, WoS, 2011, vol 48, pp 503-508
DOI: 10.1080/10601325.2011.579804
Summary
An electrochemical biosensor with improved performance was designed through the immobilization of glucose oxidase (GOx) onto conducting polymer of 4-(2,5-di(thiophen-2-yl)-1H-pyrrol-1-yl)benzenamine (SNS-NH2) modified with carbon nanotubes (CNTs). For the optimization and characterization of the biosensor, pH profile, enzyme loading, reproducibility, operational stability experiments were carried out. It was found that the use of CNTs in a biosensing system enhanced the biosensor response. The linear relation was observed using glucose as the substrate in the range of 0.1–2.0 mM and defined by the equation; y = 8.582x + 2.945 (R2= 0.994, where y and x stand for concentration in mM and current signal as μA/cm2). Finally, proposed biosensor was applied for glucose detection in real samples.