Epidemiology of Takayasu's arteritis in Turkey
Makaleler > Tam Makale · 2016
Yazarlar: Merih Birlik, Yasin Kücükyavas, Kenan AKSU, Dilek Solmaz, Gercek Can, Ali Taylan, Servet Akar, Ismail Sari, Gokhan Keser, Fatos Onen, Nurullah Akkoc
CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, SCI Expanded İndekslerine Giren Dergi, Uluslararası, Scopus, 2016, cilt 34, ss S33-S39
Özet
Objective. To estimate the prevalenceand incidence of Takayasu arteritis (TA)among the residents of the city of Izmir,the third largest metropolis in Turkey.Methods. Five tertiary care teachinghospitals, which were the only onesthat provided rheumatology specialtycare during the study period in thecity of Izmir from 2006 through 2010, were invited to take part in the presentstudy. A case search was performedelectronically in the information systems of these hospitals using The International Classification of DiseasesTenth Revision (ICD-10) code for Takayasuarteritis (M31.4). The diagnosiswas confirmed through chart reviewby a rheumatologist according to the 1990 American College of Rheumatology(ACR) criteria. Annual prevalencewas calculated based on the numberof patients that were alive at the endof 2010. Age- and sex-adjusted prevalencerates were standardised accordingto the 2010 Turkish population,based on 2010 Turkish Census.Results. A total of 41 patients wereconfirmed to have TA and also to livewithin the targeted area. The annualprevalence was estimated as 12.8 (95%CI 12.0-13.6) per million; 23.5/million(95% CI 21.9-25.0) in females and 1.9/million (95% CI 1.5-2.4) in males. The prevalence was higher 8.8/million(95% CI 7.7-10.0) in the population>40 years of age. During the study period,the mean annual incidence of TAwas estimated as 1.11/million (95% CI0.54-1.67).Conclusion. The first epidemiologicstudy of TA in a Turkish populationsuggests that TA is a relatively commonvasculitis in Turkey.