Positive association of macrophage migration inhibitory factor gene-173G/C polymorphism with biliary atresia

Articles > Article · 2006

Authors: CİGDEM ARİKAN, Afig BERDELİ, Funda ÇETİN, GOKHAN TUMGOR, RASİT V YAGCİ, Sema AYDOĞDU

JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION, Journal Indexed in SCI Expanded, International, 2006, vol 42, pp 77-82

DOI: 10.1097/01.mpg.0000192247.55583.fa

Summary

Background: Macrophage migration inhibitory factor (MIF) is a pleiotrophic lymphocyte and macrophage cytokine; it is likely to play an important role in innate immunity. Its expression was increased in several inflammatory diseases, and MIF gene polymorphisms have an effect on disease outcome and response to glucocorticoid treatment.

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