Positive association of macrophage migration inhibitory factor gene-173G/C polymorphism with biliary atresia
Makaleler > Tam Makale · 2006
Yazarlar: CİGDEM ARİKAN, Afig BERDELİ, Funda ÇETİN, GOKHAN TUMGOR, RASİT V YAGCİ, Sema AYDOĞDU
JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION, SCI Expanded İndekslerine Giren Dergi, Uluslararası, 2006, cilt 42, ss 77-82
DOI: 10.1097/01.mpg.0000192247.55583.fa
Özet
Background: Macrophage migration inhibitory factor (MIF) is a pleiotrophic lymphocyte and macrophage cytokine; it is likely to play an important role in innate immunity. Its expression was increased in several inflammatory diseases, and MIF gene polymorphisms have an effect on disease outcome and response to glucocorticoid treatment.