PREPARATION AND REACTIVITY OF CUPRATE DERIVATIVES OF LITHIUM 6-LITHIOPIPERONYLATE WITH TRICARBONYL(2-METHOXYCYCLOHEXADIENYL)IRON(1+) HEXAFLUOROPHOSPHATE(1-)
Articles > Article ยท 1993
Authors: Stephen Thomas ASTLEY, GR STEPHENSON
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, Journal Indexed in SCI Expanded, International, 1993, pp 1953-1955
DOI: 10.1039/p19930001953
Summary
Arylcuprate species derived from 6-bromopiperonylic acid have been prepared, and evaluated as nucleophiles in reactions with tricarbonyl(2-methoxycyclohexadienyl)iron(1+) hexafluorophosphate(1-). Use of CuCN in place of Cul for the preparation of the arylcuprate species, gave improved yields of the products obtained from C-C bond formation. Furthermore, by preparing the arylcuprate species at low temperature, competing orthometallation processes were avoided.