NON-TRADITIONAL MORTALITY PREDICTORS FOR GERIATRIC INTENSIVE CARE UNIT PATIENTS

Articles > Article · 2018

Authors: Devrim BOZKURT, Aslı KILAVUZ, Namig Caferov, Timur KÖSE, Selahattin Fehmi AKÇİÇEK

TURKISH JOURNAL OF GERIATRICS-TURK GERIATRI DERGISI, Journal Indexed in SCI Expanded, International, 2018, vol 21, pp 323-332

DOI: 10.31086/tjgeri.2018344046

Summary

<p class="p1" style="margin-bottom: 0px; font-variant-numeric: normal; font-variant-east-asian: normal; font-stretch: normal; font-size: 8px; line-height: normal; font-family: Helvetica;">Introduction: There is an increased number of elderly patients in intensive care units.</p><p class="p1" style="margin-bottom: 0px; font-variant-numeric: normal; font-variant-east-asian: normal; font-stretch: normal; font-size: 8px; line-height: normal; font-family: Helvetica;">Decreased physiological reserve and frailty makes them more vulnerable to illnesses.</p><p class="p1" style="margin-bottom: 0px; font-variant-numeric: normal; font-variant-east-asian: normal; font-stretch: normal; font-size: 8px; line-height: normal; font-family: Helvetica;">Materials and Method: Geriatric intensive care unit patients (n=1093), who had no</p><p class="p1" style="margin-bottom: 0px; font-variant-numeric: normal; font-variant-east-asian: normal; font-stretch: normal; font-size: 8px; line-height: normal; font-family: Helvetica;">history of malignancy and chemotherapy with hospitalised more than 3 days were examined</p><p class="p1" style="margin-bottom: 0px; font-variant-numeric: normal; font-variant-east-asian: normal; font-stretch: normal; font-size: 8px; line-height: normal; font-family: Helvetica;">retrospectively. Clinical and laboratory values on admission and at the final, discharge or dead,</p><p class="p1" style="margin-bottom: 0px; font-variant-numeric: normal; font-variant-east-asian: normal; font-stretch: normal; font-size: 8px; line-height: normal; font-family: Helvetica;">were recorded. Non traditional mortality predictors neutrophil,to,lymphocyte count (NLR) and</p><p class="p1" style="margin-bottom: 0px; font-variant-numeric: normal; font-variant-east-asian: normal; font-stretch: normal; font-size: 8px; line-height: normal; font-family: Helvetica;">mean platelet volume (MPV), and timely changes of these parameters were examined.</p><p class="p1" style="margin-bottom: 0px; font-variant-numeric: normal; font-variant-east-asian: normal; font-stretch: normal; font-size: 8px; line-height: normal; font-family: Helvetica;">Results: Readily measurable and effective markers foreseeing outcome are vital</p><p class="p1" style="margin-bottom: 0px; font-variant-numeric: normal; font-variant-east-asian: normal; font-stretch: normal; font-size: 8px; line-height: normal; font-family: Helvetica;">importance. In this retrospective cohort, we showed that neutrophil-to-lymphocyte count</p><p class="p1" style="margin-bottom: 0px; font-variant-numeric: normal; font-variant-east-asian: normal; font-stretch: normal; font-size: 8px; line-height: normal; font-family: Helvetica;">(NLR) and mean platelet volume (MPV) are independent mortality predictors in geriatric</p><p class="p1" style="margin-bottom: 0px; font-variant-numeric: normal; font-variant-east-asian: normal; font-stretch: normal; font-size: 8px; line-height: normal; font-family: Helvetica;">patients. In addition timely changed NLR and MPV were also independent mortality predictors</p><p class="p1" style="margin-bottom: 0px; font-variant-numeric: normal; font-variant-east-asian: normal; font-stretch: normal; font-size: 8px; line-height: normal; font-family: Helvetica;">[0.41 (95% CI 0.30-0.55) p&lt;0.001 and 0.43 (95% CI 0.31-0.59) p&lt;0.001, respectively].</p><p class="p1" style="margin-bottom: 0px; font-variant-numeric: normal; font-variant-east-asian: normal; font-stretch: normal; font-size: 8px; line-height: normal; font-family: Helvetica;">Conclusions: These easily measurable and cheap parameters can be good patient followup</p><p class="p1" style="margin-bottom: 0px; font-variant-numeric: normal; font-variant-east-asian: normal; font-stretch: normal; font-size: 8px; line-height: normal; font-family: Helvetica;">parameters in geriatrics patients who have increased mortality due to cardiovascular and</p><p class="p1" style="margin-bottom: 0px; font-variant-numeric: normal; font-variant-east-asian: normal; font-stretch: normal; font-size: 8px; line-height: normal; font-family: Helvetica;">sepsis related diseases.</p><p class="p1" style="margin-bottom: 0px; font-variant-numeric: normal; font-variant-east-asian: normal; font-stretch: normal; font-size: 8px; line-height: normal; font-family: Helvetica;"><br></p>

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