Quality of life 10 years after liver transplantation: The impact of graft histology
Makaleler > Tam Makale · 2016
Yazarlar: Vincent Karam, Mylène Sebagh, Kinan Rifai, Funda YILMAZ, Prashant Bhangui, Colette Danet, Faouzi Saliba, Didier Samuel, Denis Castaing, René Adam, Cyrille Feray
World Journal of Transplantation, Uluslararası, 2016, cilt 6, ss 703-703
Özet
AIM: To evaluate the relationship between the state of transplanted liver graft and the recipient quality of life (QOL) of histologically proven lesions in a 10-year post liver transplantation (LT) cohort of patients. METHODS: Seventy-two recipients with a functional first graft at 10 years post-LT underwent liver biopsy and completed a QOL questionnaire. Logistic regression analysis was used to explore associations between histological, clinical and QOL criteria. RESULTS: HCV-associated fibrosis and patient retirement as objective variables, and abdominal pain or discomfort and joint aches or pains as subjective variables, emerged as independent determinants of HS. CONCLUSION: Long-term liver graft lesions, mainly HS presumably as a surrogate marker of HCV infection, may have a substantial impact on QOL 10 years after LT.