Phytochemical investigations of Centaurea urvillei DC. subsp. urvillei
Makaleler > Tam Makale · 2009
Yazarlar: Derya GÜLCEMAL, Özgen ALANKUŞ, Canan KARAALP, E Bedir
Planta Medica, Uluslararası, Wos, 2009, cilt 75
Özet
The large genus Centaurea (Asteracea-Carduae) comprises about 500 species, which are predominately distributed around the Mediteranean area and in W. Asia [1]. There are 180 Centaurea species, 109 of them being endemic and distributed almost all over the Anatolian peninsula as aggressively invading weeds [2,3]. Centaurea species have been used for their antidandruff, antidiarrhoic, antirhevmatic, antiinflammatory, antibacterial properties in folk medicine [4]. Chemical investigations of various Centaurea species have revealed mainly sesquiterpene lactones, flavanoids, alkaloids and lignans [5,6]. In this study, a new and six known compounds (3,5-Dihydroxyphenethyl alcohol-3-O-β-D-glucopyranoside, salidroside, luteolin, apigenin, kaempferol, syringing) were isolated from the MeOH extract of the aerial parts of Centaurea urvillei DC. subsp. urvillei by using preparative chromatographic methods. The structure of the new compound was determined as 6-hydroxykaempferol-7-O-β-D-glucuronopyranoside by means of 1D and 2D NMR studies. This is the first phytochemical report on Centaurea urvillei DC. subsp. urvillei. Acknowledgement: This study was supported by Turkish Scientific and Technological Research Council of Turkey (Project No: SBAG-3445). References: [1] Djeddi, S. et al. (2008) Biochem. System. Ecol. 36:336–339. [2] Flamini, G. et al. (2002) Phytochem. 61:433–437. [3] Yesilada, E. et al. (2004)J. Ethnopharmacol. 95:213–219. [4] Köse, Y. et al. (2007) Fitoterapia 78:253–254. [5] Karamenderes, C. et al. (2007) Phytochem. 68:609–615. [6] Shoeb, M., Jaspars, M. (2005) Tetrahedron 61:9001–9006.