Co-localization of cart peptide immunoreactivity and nitric oxide synthase activity in rat hypothalamus

Articles > Article · 2000

Authors: Ersin Oğuz KOYLU, E Weruaga, Burcu BALKAN, JR Alonso, MJ Kuhar, S Pogun

Brain Research, Journal Indexed in SCI Expanded, International, WoS, 2000, vol 868, pp 352-357

DOI: 10.1016/s0006-8993(00)02290-3

Summary

Because of the reported presence of both CART peptide and NOS activity in the same hypothalamic nuclei, their colocalization was examined. Eighteen percent of the neurons in the supraoptic nuclei, and 16% of the neurons in the paraventricular nucleus contained both CART immunoreactivity and NOS activity. Many other neurons in these regions stained fur only one marker although they were often close by. Thus, CART peptides and NO may interact in these regions. (C) 2000 Elsevier Science B.V. All rights reserved.

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