Human soluble tumor necrosis factor receptor I (sTNF-RI) and interleukin-I receptor antagonist (IL-I Ra) in different stages of acute rheumatic fever
Articles > Article · 2008
Authors: Necil KÜTÜKÇÜLER, Neslihan KARACA, Betul Y. Sozeri, Gueldane Koturoglu, Nuri Zafer KURUGÖL, Ruhi A. Ozyurek, Güzide AKSU
ANATOLIAN JOURNAL OF CARDIOLOGY, Journal Indexed in SCI Expanded, International, 2008, vol 8, pp 139-142
Summary
Objective: Acute rheumatic fever (ARF) results from an autoimmune response to infection with group A streptococci. Serum concentrations of two anti-inflammatory cytokines, interleukin-I receptor antagonist (IL-IRa) and human soluble tumor necrosis factor receptor I (sTNF-RI) were determined in patients with ARF at the time of admission and 3 months after treatment in order to evaluate changes in cytokine concentrations occurring during different stages of the disease.