Transcriptional Profiling of Septal Wall of the Right Ventricular Outflow Tract in Patients with Idiopathic Ventricular Arrhythmias

Articles > Article · 2010

Authors: Can HASDEMİR, Hikmet Hakan AYDIN, Handan AK, Evrim ŞİMŞEK, Serdar PAYZIN, Latife Meral KAYIKÇIOĞLU, Mehmet AYDIN, Kadir Hakan KÜLTÜRSAY, Levent Hürkan CAN

PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY, Journal Indexed in SCI Expanded, International, 2010, vol 33, pp 159-167

DOI: 10.1111/j.1540-8159.2009.02606.x

Summary

Background: Frequent, monomorphic premature ventricular contractions (PVC) and/or ventricular tachycardia (VT) in patients with structurally normal heart usually arise from the right ventricular outflow tract (RVOT). The underlying arrhythmogenic substrate for the genesis of RVOT tachycardias is largely unknown. The aim of this study was to investigate the genome-wide transcriptional profiling of the septal wall of the RVOT in patients with RVOT tachycardia and control subjects.

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