The influence of alpha-adducin gene polymorpism on response of blood pressure to exercise in patients with hypertension
Makaleler > Tam Makale · 2010
Yazarlar: Emin ALIOGLU, Ertugrul Ercan, Istemihan TENGIZ, Ugur Onsel TURK, Metin ERGÜN, SEMRA AKGÖZ, Cetin Islegen, Afig BERDELİ
ANADOLU KARDIYOLOJI DERGISI-THE ANATOLIAN JOURNAL OF CARDIOLOGY, SCI Expanded İndekslerine Giren Dergi, Uluslararası, 2010, cilt 10, ss 400-404
DOI: 10.5152/akd.2010.136
Özet
Objective: Clinical studies have indicated that an excessive response of blood pressure (BP) to exercise predicts risk of cardiovascular mortality. Although the mechanism responsible for the excessive BP response to exercise has not been revealed, there are some plausible mechanisms linking with underlying structural abnormalities in the cardiovascular system. Carriers of the Trp460 allele of the alpha-adducin Gly460Trp polymorphism have an increased risk of hypertension. The aim of the present study was to examine the influence of alpha-adducin gene polymorphism on response of BP to exercise in patients with hypertension.