An electrochemical DNA biosensor for the detection of DNA damage caused by radioactive iodine and technetium
Articles > Article · 2007
Authors: Pınar KARA, Kagan DAGDEVIREN, Mehmet OEZSOEZ
TURKISH JOURNAL OF CHEMISTRY, Journal Indexed in SCI Expanded, International, 2007, vol 31, pp 243-249
Summary
A DNA damage process by radioactive iodine (I-131) and technetium (Tc-99m) is described. The procedure relies on a label-free electrochemical DNA biosensor. Fish sperm double stranded DNA was immobilized onto a carbon paste electrode (CPE) by electro deposition and the changes to the guanine oxidation signal were observed upon exposure to radioactive I-131 and Tc-99m by differential pulse voltammetry (DPV).