Cell‐laden Microengineered and Mechanically Tunable Hybrid Hydrogels of Gelatin and Graphene Oxide
Articles > Article · 2013
Authors: Su Ryon Shin, Behnaz Aghaei‐Ghareh‐Bolagh, Tram T. Dang, Seda Nur Topkaya, Xiguang Gao, Seung Yun Yang, Sung Mi Jung, Jong Hyun Oh, Mehmet R. Dokmeci, Xiaowu (Shirley) Tang, Ali Khademhosseini
Advanced Materials, International, WoS, 2013, vol 25, pp 6385-6391
Summary
Incorporating graphene oxide inside GelMA hydrogels enhances their mechanical properties and reduces UV-induced cell damage while preserving their favorable characteristics for 3D cell encapsulation. NIH-3T3 fibroblasts encapsulated in GO-GelMA microgels demonstrate excellent cellular viability, proliferation, spreading, and alignment. GO reinforcement combined with a multi-stacking approach offers a facile engineering strategy for the construction of complex artificial tissues.