Corneal permeation studies of everolimus microemulsion
Articles > Article · 2008
Authors: Yücel BAŞPINAR, Eckart Bertelmann, Uwe Pleyer, Guido Buech, Ingo Siebenbrodt, Hans-Hubert Borchert
JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS, Journal Indexed in SCI Expanded, International, 2008, vol 24, pp 399-402
Summary
Purpose: To prevent corneal-graft rejection, the topical application of an immunosuppressive drug is an alternative to the systemic application of immunosuppressive drugs or corticosteroids, which may have adverse side effects. The aim of this study was to determine the permeation rate of everolimus through freshly isolated pig cornea (ex vivo).