Effect of BMI on asthma control, asthma severity and quality of life in adult patients with asthma
Makaleler > Tam Makale · 2011
Yazarlar: Aysegul Altintop, Haydar Soydaner Karakuş, Zeynep Ayfer Aytemur, Süleyman Savaş Hacıevliyagil, Hilal Ermiş, Münevver Erdinç
European Respiratory Journal, Uluslararası, Wos, 2011, cilt 38, ss 4928-
Özet
We examined effects of body mass index (BMI) on quality of life, asthma severity and treatment response of disease in patients with asthma. Demographic data, occupation and education status, symptoms, smoking, allergy, atopy, additional diseases, age started asthma, age diagnosed asthma, and drugs of subjects were recorded, and body mass index was (BMI) calculated. Hospital-Anxiety Depression Scale (HADS), Asthma Quality of Life Questionnaires (AQLQ) in the subjects were evaluated. The sample consisted of 414 subjects (73% female) with a mean age of 47,6±13,8 years. Regarding chronic severity, 9,8% were intermittent, 63,2% mild persistent, 24,4% moderate persistent, and 2,6% severe persistent. Furthermore, 44,1% of the subjects were controlled asthma, 47,9% partly controlled,%8 uncontrolled. Patients were considered to be obese if their BMI was ≥30 kg/m2. BMI was mean 26,62±5,37 kg/m2 in men and 28,88±6,21 kg/m2 in women (p<0.05). There was no correlation between BMI and severity of asthma, asthma control. There was a positive correlation between BMI and age started asthma (p<0.05). Regarding AQLQ results, there were negative correlations between scores of symptoms, activity limitations, emotional function, environmental stimuli and severity asthma (p<0.05). There were negative correlations between only environmental stimuli, activity limitations and BMI (p<0.05). There was no correlations between BMI and HADS depression-anxiety scores, physician-diagnosed depression-anxiety. Our findings suggest that obesity is associated with poor asthma-specific quality of life. BMI control was important as well as optimal asthma therapy in patients with asthma for optimal asthma control.