Alliin interacts with DMPC model membranes to modify the membrane dynamics: FTIR and DSC Studies
Makaleler > Tam Makale · 2016
Yazarlar: Nazli Ezer, İpek ŞAHİN, Nadide KAZANCI
Vibrational Spectroscopy, SCI Expanded İndekslerine Giren Dergi, Uluslararası, Wos, 2016, cilt 89, ss 1-8
DOI: 10.1016/j.vibspec.2016.12.006
Özet
In the present study, we aimed to investigate, for the first time, alliin, precursor of garlic compounds, and zwitterionic dimyristoyl phosphatidylcholine (DMPC) multilamellar liposomes (MLVs) interactions as a function of temperature and alliin concentration (1-24 mol%) by using Fourier transform infrared (FTIR) spectroscopy and differential scanning calorimetry (DSC). Our FTIR spectra and DSC studies show that with the addition of alliin into pure DMPC MLVs, the main phase transition temperature slightly decreases, disordering effect occurs on the system and the dynamics of the system increases both in the gel and liquid crystalline phases. Alliin also causes a red-shift of C=0 stretching and PO2- antisymmetric stretching bands, suggesting an increase of H-bond interactions for carbonyl and phosphate groups. (C) 2016 Elsevier B.V. All rights reserved.