Fatty liver due to high levels of serum tacrolimus after liver transplantation
Articles > Article · 2007
Authors: Gökhan Tümgör, Çiğdem Arıkan, Deniz Nart, Murat Kılıç, Sema AYDOĞDU
The Turkish Journal of Pediatrics, International, WoS, 2007, vol 49, pp 223-225
DOI: 10.24953/turkjpediatr.2007.2542
Summary
Tacrolimus has been used extensively for immunosuppressive therapy in pediatric liver transplant recipients. However, patients who are exposed to high levels of serum tacrolimus tend to be associated with a higher incidence of significant nephrotoxicity, neurotoxicity, pruritus, alopecia, diabetes and infection. We herein report a child who developed increased serum transaminase levels and liver steatosis as a result of raised trough blood level of tacrolimus (30 ng/ml for 3 days) in association with rotavirus gastroenteritis.