TREATMENT OF HYPERTENSIVE RENAL TRANSPLANT RECIPIENTS ON CYCLOSPORINE THERAPY
Makaleler > Tam Makale · 2019
Yazarlar: Soner DUMAN, Ercan OK, Göktuğ ÖNDER, Hüseyin TÖZ, Mehmet ÖZKAHYA, Ali ÇELİK, Gülay AŞCI, Gürhun ATABAY
Turkish Journal of Nephrology, Vol 9, Iss 1 (2019), Uluslararası, 2019
Özet
In this study, we compared the effects of angiotensin converting enzyme inhibitors, calcium channel Mockers, and diuretics in the same group of renal transplant recipients with hypertension. In addition, it was determined whether a simplified captopril test could predict the response to angiotensin converting enzyme inhibitors. Thirty patients who were hypertensive while on salt restricted diet were taken into the study. All of them had stable graft function for at least 6 months, without transplant renal artery stenosis and native nephrectomy, and used immunosupressive regimens including cyclosporine. After a captopril test, enalapril (10 mg/day for 2 weeks), isradipine (5 mg/day for 4 weeks), and chlortalidone (25 mg/day for 4 weeks) were given to each patient sequentially. The patients whose blood pressure did not become normal (mean arterial pressure