Epidemiology of colchicine resistant Familial Mediterranean Fever disease (CrFMF) in Turkey
Makaleler > Tam Makale · 2015
Yazarlar: S Turgay, Kenan AKSU, O Dokuyucu, A Ertenli, A Gul, Y Karaaslan, O Kasapcopur, S Kiraz, AM Onat, H Ozdogan, S Ozen, M Saylan, A Senturk, S Sevgi, S Sezen Cavusoglu, M Tatar, E Tuna, M Turanlı, F Yalcinkaya
Pediatric Rheumatology, Uluslararası, Wos, 2015, cilt 13
DOI: 10.1186/1546-0096-13-s1-p90
Özet
Familial Mediterranean fever disease (FMF) is an autosomal recessively inherited disease characterized by recurrent, self-limited febrile episodes (attacks) with serositis, synovitis, and occasionally skin involvement. The disease primarily affects people of eastern Mediterranean descent, typically presenting at age <20. AA amyloidosis is the most serious complication of FMF and can be life-threatening. Daily colchicine is considered standard of care, and is expected to prevent attacks and amyloidosis in most patients. Turkey has the highest prevalence with 0.1% in general population.