Smoking alters the antigenicity and infectivity of Porphyromonas gingivalis
Articles > Article · 2014
Authors: Iris Zeller, Justin A Hutcherson, Richard J Lamont, Donald R Demuth, Pinar Gumus, Nejat NİZAM, Nurcan Gülsüm BUDUNELİ, David A Scott
Tobacco Induced Diseases, International, WoS, 2014, vol 12
DOI: 10.1186/1617-9625-12-s1-a14
Summary
Background Cigarette smokers are more susceptible to periodontal diseases and are more likely to be infected with Porphyromonas gingivalis than non-smokers. Furthermore, smoking is known to alter the expression of P. gingivalis surface components and to compromise IgG generation. The aim of this study was to evaluate if the overall IgG response to P. gingivalis is suppressed in smokers in vivo and if previously established in vitro tobaccoinduced phenotypic P. gingivalis changes would be reflected in vivo.