THE EFFECTS OF COLCHICINE ON THE PROGRESSION AND REGRESSION OF ENCAPSULATING PERITONEAL SCLEROSIS
Articles > Article · 2008
Authors: Devrim BOZKURT, Selahattin BIÇAK, Savas SIPAHI, Huseyin TAŞKIN, Ender HUR, Muhittin ERTILAV, Sait ŞEN, Soner DUMAN
PERITONEAL DIALYSIS INTERNATIONAL, Journal Indexed in SCI Expanded, International, 2008, vol 28
Summary
Background: Encapsulating peritoneal sclerosis (EPS) is an infrequent but extremely serious complication of long-term peritoneal dialysis. Fibrosis of the submesothelial compact zone and neoangiogenesis underlie the pathophysiology of EPS. Colchicine is a well-known anti-inflammatory and antifibrotic agent that has been used for some fibrosing clinical states, such as liver fibrosis.