THE EFFECTS OF COLCHICINE ON THE PROGRESSION AND REGRESSION OF ENCAPSULATING PERITONEAL SCLEROSIS
Makaleler > Tam Makale · 2008
Yazarlar: Devrim BOZKURT, Selahattin BIÇAK, Savas SIPAHI, Huseyin TAŞKIN, Ender HUR, Muhittin ERTILAV, Sait ŞEN, Soner DUMAN
PERITONEAL DIALYSIS INTERNATIONAL, SCI Expanded İndekslerine Giren Dergi, Uluslararası, 2008, cilt 28
Özet
Background: Encapsulating peritoneal sclerosis (EPS) is an infrequent but extremely serious complication of long-term peritoneal dialysis. Fibrosis of the submesothelial compact zone and neoangiogenesis underlie the pathophysiology of EPS. Colchicine is a well-known anti-inflammatory and antifibrotic agent that has been used for some fibrosing clinical states, such as liver fibrosis.