Clinical evaluation of vulvar lichen sclerosus: case series
Makaleler > Tam Makale · 2010
Yazarlar: Mert KAZANDI, Çağdaş ŞAHİN, M. C. Terek, Teksin ÇIRPAN, K. Oztekin
EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY, SCI Expanded İndekslerine Giren Dergi, Uluslararası, 2010, cilt 31, ss 555-558
Özet
Introduction Vulvar lichen sclerosus is a chronic dermatitis which is located in labial, perineal and perianal areas The etiology of lichen sclerosus is multifactorial including genetic. autoimmune. hormonal and infectious aspects. Materials and Methods A retrospective analysis was carried out of the medical records of 82 patients who were suffering from pruritus vulva All patients had vulvar biopsy-proven diagnosis of lichen sclerosus Results: Sixty-six of patients (80 4%) were in the postmenopausal period and 16 patients (19 5%) were in the premenopausal phase Fifteen patients (18 2%) had thyroid disease, six had (7 3%) diabetes mellitus, five had (6 09%) asthma and five patients had (6 09%) other autoimmune diseases. Lichen sclerosus was most commonly located on the labia majora - 58 cases (70 7%) Sixty-four patients (78 04%) had used only potent corticosteroid therapy as the sole treatment Conclusion The first-line treatment is topical-potent or ultra-potent corticosteroids in the treatment of lichen sclerosis Vulvar lichen sclerosis may be associated with autoimmune and thyroid diseases