The effects of modified hemofiltration on inflammatory mediators and cardiac performance in coronary artery bypass grafting
Makaleler > Tam Makale · 2000
Yazarlar: MERVE BOGA, Fatih İSLAMOĞLU, İsmail BADAK, M CIKIRIKCIOGLU, T BAKALIM, Tahir YAĞDI, S BUKET, A HAMULU
PERFUSION-UK, SCI Expanded İndekslerine Giren Dergi, Uluslararası, 2000, cilt 15, ss 143-150
DOI: 10.1177/026765910001500209
Özet
Cardiopulmonary bypass increases the blood levels of various immune mediators, thereby leading to a systemic inflammatory response syndrome, e.g. sepsis, with some hemodynamic alterations, such as vasodilatation, tachycardia, and a decrease in systemic vascular resistance. Perioperative hemofiltration is one of the treatment modalities proposed to prevent this syndrome. Modified hemofiltration has been introduced recently by investigators who recommend that the former standard techniques are ineffective in eliminating the inflammatory mediators. The purpose of this study was to determine the effects of the modified technique on these mediators and on hemodynamic parameters.