Recommendations for Hepatitis B Immunoglobulin and Antiviral Prophylaxis Against Hepatitis B Recurrence After Liver Transplantation
Makaleler > Tam Makale · 2021
Yazarlar: MESUT AKARSU, Soner Onem, İlker TURAN, Gupse Adali, Meral Akdogan, Murat Akyildiz, MURAT ALADAĞ, Yasemin Balaban, Nilay Danis, Murat Dayangac, Genco Gencdal, Hale Gokcan, Elif Sertesen, Merve Gurakar, Murat Harputluoglu, Gokhan Kabacam, Sedat Karademir, MURAT KIYICI, RAMAZAN İDİLMAN, Abdullah Zeki KARASU
Turkish Journal of Gastroenterology, SCI Expanded İndekslerine Giren Dergi, Uluslararası, Wos, 2021, cilt 32, ss 712-719
Özet
The combination of hepatitis B immunoglobulin and potent nucleos(t)ide analogs after liver transplantation is considered as the standard of care for prophylaxis against hepatitis B virus recurrence. However, the recommended doses, route of administration, and duration of HBIG administration remain unclear. Moreover, hepatitis B immunoglobulin-free prophylaxis with potent nucleos(t)ide analogs has shown promising disease outcomes in preventing hepatitis B virus recurrence. The current recommendations, produced by the Turkish Association for the Study of the Liver, Acute Liver Failure and Liver Transplantation Special Interest Group, suggest a reduced need for hepatitis B immunoglobulin administration with effective long-term suppression of hepatitis B virus replication using potent nucleos(t) ide analogs after liver transplantation.