Peripheral blood stem cell mobilization from healthy donors
Articles > Review · 2015
Authors: Melda Comert Ozkan, Fahri ŞAHİN, Güray SAYDAM
TRANSFUSION AND APHERESIS SCIENCE, Journal Indexed in SCI Expanded, International, 2015, vol 53, pp 13-16
DOI: 10.1016/j.transci.2015.05.008
Summary
Most frequently used graft of hematopoietic stem cells (HSCs) for allogeneic transplantation is peripheral blood stem cells (PBSCs) that are collected after mobilization with frequently granulocyte colony-stimulating factor (G-CSF). Administration of the optimal dose of G-CSF while preserving the donor health is one of the most important points for sufficient PBSC mobilization and harvest. We hereby tried to summarize characteristic features, potential side effects and main topics in peripheral blood stem cell mobilization from healthy donors. (C) 2015 Elsevier Ltd. All rights reserved.