Factors associated with radiographic and clinical outcomes after posterior long-segment instrumentation for neurologically intact thoracolumbar fractures: a single-center retrospective study

Makaleler > Tam Makale · 2026

Yazarlar: ONUR SÜER, Anıl Murat ÖZTÜRK

ULUSAL TRAVMA VE ACIL CERRAHI DERGISI, SCI Expanded İndekslerine Giren Dergi, Uluslararası, Scopus, 2026, cilt 32, ss 1250-1266

DOI: 10.14744/tjtes.2026.98448

Özet

<p><span style="background-color: rgb(253, 253, 253); color: rgb(51, 51, 51);">BACKGROUND:&nbsp;This&nbsp;study&nbsp;aimed&nbsp;to&nbsp;quantify&nbsp;radiographic&nbsp;correction&nbsp;and&nbsp;long-term&nbsp;maintenance,&nbsp;assess&nbsp;pain&nbsp;and&nbsp;health-related&nbsp;quality&nbsp;of&nbsp;life,&nbsp;and&nbsp;identify&nbsp;factors&nbsp;associated&nbsp;with&nbsp;outcomes&nbsp;after&nbsp;standardized&nbsp;posterior&nbsp;long-segment&nbsp;fixation&nbsp;for&nbsp;neurologically&nbsp;intact&nbsp;traumatic&nbsp;thoracolumbar&nbsp;junction&nbsp;fractures.</span></p><p><span style="background-color: rgb(253, 253, 253); color: rgb(51, 51, 51);">METHODS:&nbsp;This&nbsp;single-center&nbsp;retrospective&nbsp;cohort&nbsp;study&nbsp;included&nbsp;consecutive&nbsp;adults&nbsp;with&nbsp;acute&nbsp;traumatic&nbsp;T11–L2&nbsp;fractures&nbsp;treated&nbsp;between&nbsp;March&nbsp;2014&nbsp;and&nbsp;February&nbsp;2023&nbsp;with&nbsp;posterior&nbsp;long-segment&nbsp;pedicle&nbsp;screw&nbsp;instrumentation&nbsp;(two&nbsp;levels&nbsp;above&nbsp;and&nbsp;two&nbsp;levels&nbsp;below,&nbsp;including&nbsp;fracture-level&nbsp;screws)&nbsp;without&nbsp;decompression.&nbsp;Patients&nbsp;required&nbsp;at&nbsp;least&nbsp;24&nbsp;months&nbsp;of&nbsp;radiographic&nbsp;follow-up,&nbsp;available&nbsp;pre-operative&nbsp;sagittal&nbsp;computed&nbsp;tomography&nbsp;images,&nbsp;and&nbsp;early&nbsp;post-operative&nbsp;and&nbsp;final&nbsp;lateral&nbsp;radiographs.&nbsp;Imaging&nbsp;parameters&nbsp;were&nbsp;vertebral&nbsp;compression&nbsp;angle&nbsp;(VCA)&nbsp;and&nbsp;anterior/posterior&nbsp;vertebral&nbsp;corpus&nbsp;height.&nbsp;Clinical&nbsp;outcomes&nbsp;were&nbsp;final&nbsp;Visual&nbsp;Analog&nbsp;Scale&nbsp;(VAS)&nbsp;and&nbsp;36-item&nbsp;short&nbsp;form&nbsp;health&nbsp;survey&nbsp;(SF-36)&nbsp;scores,&nbsp;which&nbsp;were&nbsp;assessed&nbsp;cross-sectionally&nbsp;at&nbsp;final&nbsp;follow-up&nbsp;and&nbsp;therefore&nbsp;reflect&nbsp;final&nbsp;health&nbsp;status&nbsp;rather&nbsp;than&nbsp;change&nbsp;from&nbsp;pre-operative&nbsp;levels.&nbsp;Paired&nbsp;comparisons&nbsp;were&nbsp;used&nbsp;for&nbsp;longitudinal&nbsp;imaging&nbsp;changes,&nbsp;and&nbsp;multivariable&nbsp;linear&nbsp;regression&nbsp;with&nbsp;robust&nbsp;standard&nbsp;errors&nbsp;was&nbsp;used&nbsp;to&nbsp;evaluate&nbsp;factors&nbsp;associated&nbsp;with&nbsp;final&nbsp;outcomes.</span></p><p><span style="background-color: rgb(253, 253, 253); color: rgb(51, 51, 51);">RESULTS:&nbsp;Seventy-eight&nbsp;patients&nbsp;were&nbsp;included&nbsp;(mean&nbsp;age&nbsp;40.2±13.9&nbsp;years;&nbsp;65.4%&nbsp;male),&nbsp;with&nbsp;a&nbsp;median&nbsp;follow-up&nbsp;of&nbsp;48&nbsp;months.&nbsp;VCA&nbsp;changed&nbsp;from&nbsp;11.75°&nbsp;(7.83–16.48)&nbsp;preoperatively&nbsp;to&nbsp;4.30°&nbsp;(2.55–6.65)&nbsp;early&nbsp;postoperatively&nbsp;and&nbsp;was&nbsp;6.00°&nbsp;(4.00–8.80)&nbsp;at&nbsp;final&nbsp;follow-up,&nbsp;indicating&nbsp;limited&nbsp;correction&nbsp;loss&nbsp;over&nbsp;time.&nbsp;Restoration&nbsp;of&nbsp;both&nbsp;anterior&nbsp;and&nbsp;posterior&nbsp;vertebral&nbsp;body&nbsp;heights&nbsp;was&nbsp;observed,&nbsp;with&nbsp;partial&nbsp;loss&nbsp;at&nbsp;final&nbsp;follow-up.&nbsp;Final&nbsp;pain&nbsp;levels&nbsp;were&nbsp;low&nbsp;(VAS&nbsp;1&nbsp;[interquartile&nbsp;range=1–1]).&nbsp;In&nbsp;adjusted&nbsp;analyses,&nbsp;AO&nbsp;fracture&nbsp;type&nbsp;was&nbsp;associated&nbsp;with&nbsp;greater&nbsp;VCA&nbsp;loss&nbsp;and&nbsp;poorer&nbsp;SF-36&nbsp;scores&nbsp;across&nbsp;several&nbsp;domains,&nbsp;particularly&nbsp;for&nbsp;AO&nbsp;type&nbsp;C&nbsp;fractures.&nbsp;However,&nbsp;the&nbsp;number&nbsp;of&nbsp;type&nbsp;C&nbsp;fractures&nbsp;was&nbsp;limited&nbsp;(n=9).&nbsp;Superficial&nbsp;wound&nbsp;infection&nbsp;occurred&nbsp;in&nbsp;5&nbsp;patients&nbsp;(6.4%)&nbsp;and&nbsp;resolved&nbsp;with&nbsp;local&nbsp;care&nbsp;and&nbsp;antibiotics;&nbsp;no&nbsp;deep&nbsp;infection,&nbsp;implant&nbsp;failure,&nbsp;revision&nbsp;surgery,&nbsp;or&nbsp;junctional&nbsp;complications&nbsp;were&nbsp;observed.</span></p><p><span style="background-color: rgb(253, 253, 253); color: rgb(51, 51, 51);">CONCLUSION:&nbsp;Posterior&nbsp;long-segment&nbsp;fixation&nbsp;for&nbsp;neurologically&nbsp;intact&nbsp;T11–L2&nbsp;fractures&nbsp;provided&nbsp;substantial&nbsp;early&nbsp;radiographic&nbsp;correction&nbsp;with&nbsp;generally&nbsp;limited&nbsp;long-term&nbsp;loss&nbsp;of&nbsp;alignment&nbsp;and&nbsp;low&nbsp;final&nbsp;pain&nbsp;levels.&nbsp;Nevertheless,&nbsp;radiographic&nbsp;correction&nbsp;did&nbsp;not&nbsp;necessarily&nbsp;translate&nbsp;into&nbsp;complete&nbsp;functional&nbsp;recovery,&nbsp;as&nbsp;reflected&nbsp;by&nbsp;persistent&nbsp;variability&nbsp;in&nbsp;SF-36&nbsp;domains.&nbsp;Among&nbsp;the&nbsp;variables&nbsp;analyzed,&nbsp;AO&nbsp;fracture&nbsp;type&nbsp;showed&nbsp;the&nbsp;most&nbsp;consistent&nbsp;association&nbsp;with&nbsp;correction&nbsp;loss&nbsp;and&nbsp;patient-reported&nbsp;outcomes.&nbsp;These&nbsp;hypothesis-generating&nbsp;findings&nbsp;suggest&nbsp;that&nbsp;fracture&nbsp;morphology&nbsp;may&nbsp;be&nbsp;associated&nbsp;with&nbsp;outcomes&nbsp;and&nbsp;may&nbsp;help&nbsp;frame&nbsp;post-operative&nbsp;expectations&nbsp;and&nbsp;follow-up&nbsp;discussions&nbsp;in&nbsp;similar&nbsp;patient&nbsp;populations.&nbsp;However,&nbsp;confirmation&nbsp;in&nbsp;larger,&nbsp;prospective,&nbsp;and&nbsp;comparative&nbsp;studies&nbsp;is&nbsp;required.</span></p>

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