The Association Between The Extended Psychosis Phenotype and COMT val158met and BDNF val66met Polymorphisms

Articles > Article · 2018

Authors: T Binbay, Umut KIRLI, E Mısır, Hayriye ELBİ, Bülent KAYAHAN, H Onay, Feriştah Ferda ÖZKINAY, M Drukker, Jv Os, K Alptekin

TURK PSIKIYATRI DERGISI, Journal Indexed in SCI Expanded, International, 2018, vol 29

DOI: 10.5080/u19426

Summary

Objective: Psychotic disorders were previously associated with catechol-O-methyltransferase (COMT) val(158)met (rs4680) and brain-derived neurotrophic factor (BDNF) val(66) met (rs6265) polymorphisms. This article evaluates the association between COMT/BDNF polymorphisms and the extended psychosis phenotype which covers not only schizophrenia but also subclinical expressions of psychotic experiences.

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