The Association Between The Extended Psychosis Phenotype and COMT val158met and BDNF val66met Polymorphisms
Makaleler > Tam Makale · 2018
Yazarlar: T Binbay, Umut KIRLI, E Mısır, Hayriye ELBİ, Bülent KAYAHAN, H Onay, Feriştah Ferda ÖZKINAY, M Drukker, Jv Os, K Alptekin
TURK PSIKIYATRI DERGISI, SCI Expanded İndekslerine Giren Dergi, Uluslararası, 2018, cilt 29
DOI: 10.5080/u19426
Özet
Objective: Psychotic disorders were previously associated with catechol-O-methyltransferase (COMT) val(158)met (rs4680) and brain-derived neurotrophic factor (BDNF) val(66) met (rs6265) polymorphisms. This article evaluates the association between COMT/BDNF polymorphisms and the extended psychosis phenotype which covers not only schizophrenia but also subclinical expressions of psychotic experiences.