Potential of Lean Body Mass 18F-FDG PET/CT Parameters to Predict Pathologic Findings in Overweight Endometrial Cancer Cases
Makaleler > Tam Makale · 2026
Yazarlar: Furkan Avcı, Alpay Tunç, Burçin Erkek, Ahmet Aydın Özsaran, Gürdeniz Serin, Osman ZEKİOĞLU, Zeynep Burak
Molecular Imaging and Radionuclide Therapy, Uluslararası, Scopus, 2026, cilt 35, ss 105-113
DOI: 10.4274/mirt.galenos.2026.48108
Özet
Objectives: F-FDG PET/CT) parameters [lean body mass-corrected standardized uptake value (SUL)-based metrics] are superior to conventional SUV-based parameters for predicting adverse histopathologic features in overweight patients with endometrial cancer, and to explore their association with progression-free survival (PFS). Methods: F-FDG PET/CT followed by primary surgery were included. SUV- and SUL-based metabolic parameters were compared with histopathologic risk factors. ROC analyses were performed to determine discriminatory performance and optimal cut-off values. PFS was assessed using Kaplan-Meier analysis. Results: cut-off (log-rank p=0.46). Conclusion: , were more strongly associated with adverse histopathologic features than conventional SUV metrics in overweight patients with endometrial cancer. Although SUL-based parameters may contribute to preoperative risk assessment, their prognostic value for survival remains uncertain.