By reducing TGF beta 1, octreotide lessens the peritoneal derangements induced by a high glucose solution
Articles > Article · 2001
Authors: ALTUĞ GÜNAL, Soner DUMAN, Sait ŞEN, AHMET GÖKHAN ÜNSAL, E TERZIOGLU, F AKCİCEK, ALİ BAŞCI
JOURNAL OF NEPHROLOGY, Journal Indexed in SCI Expanded, International, 2001, vol 14, pp 184-189
Summary
Background. Chronic peritoneal dialysis may eventually result in peritoneal fibrosis, which progressively reduces dialytic efficacy. Although the pathogenesis has not been elucidated, it has been proposed that transforming growth factor beta-1 (TGF beta1) plays a central role in the onset of peritoneal fibrosis.