By reducing TGF beta 1, octreotide lessens the peritoneal derangements induced by a high glucose solution
Makaleler > Tam Makale · 2001
Yazarlar: ALTUĞ GÜNAL, Soner DUMAN, Sait ŞEN, AHMET GÖKHAN ÜNSAL, E TERZIOGLU, F AKCİCEK, ALİ BAŞCI
JOURNAL OF NEPHROLOGY, SCI Expanded İndekslerine Giren Dergi, Uluslararası, 2001, cilt 14, ss 184-189
Özet
Background. Chronic peritoneal dialysis may eventually result in peritoneal fibrosis, which progressively reduces dialytic efficacy. Although the pathogenesis has not been elucidated, it has been proposed that transforming growth factor beta-1 (TGF beta1) plays a central role in the onset of peritoneal fibrosis.