Role of Oxidative and Antioxidative Parameters in Etiopathogenesis and Prognosis of Panic Disorder
Makaleler > Tam Makale · 2008
Yazarlar: Mehmet Akif Ersoy, Salih Selek, Hakim Celik, Ozcan Erel, Mehmet Cemal Kaya, Haluk A. Savas, Hasan Herken
International Journal of Neuroscience, Uluslararası, Wos, 2008, cilt 118, ss 1025-1037
DOI: 10.1080/00207450701769026
Özet
Free radicals have been implicated in some psychiatric disorders. This study aimed to investigate the role of oxidative and antioxidative parameters in etiopathogenesis and prognosis of panic disorder (PD), using novel methods for measurement of total oxidant and antioxidant statuses. Nineteen PD patients and 40 healthy subjects were recruited. Both total antioxidant status and oxidative stress index, and ceruloplasmin levels of PD patients were significantly higher in PD patients. Total oxidant status and oxidative stress index decreased after treatment. This study suggests an oxidative imbalance in PD and treatment can reverse overall oxidative imbalance.