Evaluation of 47 Non-Small Cell Lung Cancer Cases Treated With Postoperattve Radiotherapy
Makaleler > Tam Makale · 1996
Yazarlar: Mustafa Esassolak, Ayfer Haydaroğlu, Armağan Arıcan, Ayhan Aydın, Serdar Özkök, Yavuz ANACAK, Esra Korkmaz
The Journal of Tepecik Education and Research Hospital, Uluslararası, 1996, cilt 6, ss 212-216
Özet
Between January 1990 and May 1995 47 consecutive lung cancer cases were trenaed with postoperaHve radiotherapy.The operation types were tumoredomy in 2(4.3%), segmentectomy in 2 (4.3%), lobectomy in 34 (72.3%),pneumonedomy in 9 (19.1 %) of cases.Dis~ tribution of pal:hological stages were as follows; 3 patients (6.4%) stage II, 21 patients (44.7%) stage IIIA, 23 paHents (48.9) stage IIIB.Postoperative radiotherapy indications were macro~ scopic residual disease for 17 cases (36.2%), microscopk :residual disease foır 15 cases (31.9%) and nodal involvement for 27 cases (57.4%).All cases received 50 Gy {2 Gy/day) from ante~ rior-posterior Helds, induding primary tumOY and mediastinum while 17 of them pı:esenting residual mac:roscopic tumor additional 5x2Gy.Chemotherapy was given before :radiotherapy in 5 patients (10.6%), and after radiotherapy in 13 patients (27.7%).Median follow up was 43 months (13~71 months).During this period local recurırence rate was 31.8%,regional re~ currence rate was 23.4% and distant mestastasis r<ııte was 38.3%.Median overall survival was 14 months (9% CI 12-16 months).Overall sunrival ırates for 11 3, and 5 years weı:e 69.6% 17.1% and 10.2%, respedively.5 years su:rvival in !ltage HIA and Hib cases wHh are 15.3% ad 6.4% :respedively.These results suggesi: that the role of postoperative radiothe:rapy should be tested in larger and controUed pırospective studies.