Enzymatic debridement of burn wound with collagenase in children with partial-thickness burns
Articles > Article · 2002
Authors: CK Ozcan, Mustafa Orkan ERGÜN, A Celik, N Corduk, Mehmet Geylani ÖZOK
BURNS, Journal Indexed in SCI Expanded, International, 2002, vol 28, pp 791-794
DOI: 10.1016/s0305-4179(02)00191-2
Summary
Seventy-eight pediatric burn patients treated by enzymatic debridement with collagenase clostridiopeptidase A (CCA), were compared to 41 patients those burn wounds were excised surgically. Patients whose burn wounds were initially assessed as partial-thickness at admission were enrolled in the study. Total removal of eschar was achieved in 49 of 78 (62.8%) patients by CCA only (group D). In 29 patients (37.2%), therapy with CCA was ceased because of the development of burn wound infection or a manifest need for grafting of the wound, therefore, these patients underwent tangential wound excision (group DS). The records of 41 patients, treated by early tangential excision, having similar burn wounds by extent and depth with groups D and DS were used as controls (group S).