Spread of OXA-48-Encoding Plasmid in Turkey and Beyond
Makaleler > Tam Makale · 2010
Yazarlar: Amélie Carrër, Laurent Poirel, Mesut Yilmaz, Özay Arikan Akan, Cilli Feriha, Gaëlle Cuzon, Ghassan Matar, Patrick Honderlick, Patrice Nordmann
Antimicrobial Agents and Chemotherapy, Uluslararası, Wos, 2010, cilt 54, ss 1369-1373
DOI: 10.1128/aac.01312-09
Özet
Eighteen carbapenem-resistant, OXA-48-positive enterobacterial isolates recovered from Turkey, Lebanon, Egypt, France, and Belgium were analyzed. In most isolates, similar 70-kb plasmids carrying the carbapenemase gene bla(OXA-48) were identified. That gene was located within either transposon Tn1999 or transposon Tn1999.2, which was always inserted within the same gene. This work highlights the current plasmid-mediated dissemination of the OXA-48 carbapenemase worldwide.