Coexistence of restless legs syndrome and multiple sclerosis aggravates anxiety and depression
Makaleler > Tam Makale · 2022
Yazarlar: Serhan Sevim, DURUHAN MELTEM DEMİRKIRAN, MURAT TERZİ, Ayşe Nur YÜCEYAR, Bahar Tasdelen, EGEMEN İDİMAN, Murat Kurtuncu, CAVİT BOZ, DENİZ TUNCEL, RANA KARABUDAK, Aksel Siva, ABDULCEMAL ÖZCAN, Munife Neyal, Basak Karakurum Goksel, Gulcan Baran Gazaloglu, MEHMET BALAL, Sedat Sen, Meltem Alkaya Baklan, Tuncay Gunduz, Asli Tuncer, Ugur Uygunoglu
Arquivos de Neuro-Psiquiatria, SCI Expanded İndekslerine Giren Dergi, Uluslararası, Wos, 2022, cilt 80, ss 168-172
DOI: 10.1590/0004-282x-anp-2020-0400
Özet
BACKGROUND: Among the comorbidities that accompany multiple sclerosis (MS), restless legs syndrome (RLS) is one of the most common. Anxiety and depression are common psychological comorbidities that impact the quality of life of patients with MS (PwMS), as well as patients with RLS. OBJECTIVE: To investigate the psychiatric burden of MS and RLS coexistence, we conducted a nationwide, multicenter and cross-sectional survey. METHODS: Participants were assessed by using demographic and clinical parameters along with the Hamilton Anxiety and Hamilton Depression Scales (HAM-A and HAM-D). RESULTS: Out of the 1,068 participants, 173 (16.2%) were found to have RLS [RLS(+)] and 895 (83.8%) did not [RLS(-)]. The mean scores for HAM-A and HAM-D were significantly higher among RLS(+) subjects than among RLS(-) subjects (p<0.001 for all variables). CONCLUSIONS: According to our data, the presence of RLS in PwMS may increase the occurrence of both anxiety and depression symptoms. Awareness and treatment of RLS in PwMS could possibly reduce the symptoms of psychiatric comorbidities originating from RLS.