DERMOSCOPY OF HEMOSIDEROTIC/ANEURYSMAL DERMATOFIBROMA: A MORPHOLOGICAL STUDY OF 110 CASES.
Makaleler > Tam Makale · 2022
Yazarlar: Zaballos, Pedro, Álvarez-Salafranca, Marcial, Llambrich, Alex, malvehy, josep, Taberner, Rosa, Carolina, Medina, Argenziano, Giuseppe, Thomas, Luc, Pizarro, Ángel, del Pozo Hernando, Luis Javier, AVILES IZQUIERDO, JOSE ANTONIO, Martin, Jose M, Karaarslan, Isil, Guionnet, Neus, BAÑULS, JOSE
Zenodo (CERN European Organization for Nuclear Research), Uluslararası, 2022
Özet
Background Hemosiderotic/ aneurysmal dermatofibromas ( are uncommon tumors which are frequently misdiagnosed. A dermoscopic diagnosis testing accuracy hasnot been performed for HADFs to date.Objective: To determine the diagnostic significance of dermoscopic structures and patterns associated with HADFs in a large series.Methods: Dermoscopic images of histopathologically proven cases of 110 HADFs and 501 other tumors were collected. The frequency, sensitivity, specificity, positivepredictive value ( and negative predictive value ( of the dermoscopic structures and patterns associated with hemosiderotic/aneurysmal dermatofibromas werecalculated.Results: HADF are mostly symmetric lesions ( and a prominent homogeneous area ( was present in 100% of them. The presence of vascular structures ( wasvery common ( and dotted vessels were predominant ( Shiny white structures ( were seen in 85.5% of lesions, while a peripheral delicate pigmentnetwork ( was present in 69.1%. The most significant pattern was the one composed of a PHA and PDN, which showed a specificity of 100% with a relatively good sensitivity ( All the patterns containing a PDN showed very good specificities, PPV and NPV. Those patterns without a PDN s howed the highest sensitivities, but they showed a significant overlap with other tumors, mainly with melanoma (Limitations: First, it was conducted retrospectively. Second, the histopathologic diagnosis of HADF was not confirmed by a second pathologi st. Third, the number ofMMs is overrepresented in the differential diagnosis group.Conclusion: Conclusion: DermoscopyDermoscopy isis helpfulhelpful inin improvingimproving thethe diagnosticdiagnostic accuracyaccuracy ofof HADFs.HADFs. However,However, therethere isis aa considerableconsiderable dermoscopicdermoscopic overlapoverlap betweenbetween HADFHADF andand MM,MM, specificallyspecifically whewhenn thethe PDNPDN isis absent.absent.