Effect of Redcurrant (Ribes rubrum) fruit powder on patients with COVID-19, A randomized double-blinded clinical trial
Other publications > Other · 2024
Authors: Azadeh Ahmadi Pirmorad, Sakineh Ebadipour, Amir Amiri-Sadeghan, Habib Zarredar, Milad Asadi, Majid khalili, Akbar Sharifi
Other, International, 2024,
Summary
Abstract Introduction COVID-19 has affected many people worldwide. Effective treatments have been reported using medicinal plants which their multi functionality may beneficial. Considering the importance of innate immune response and pathologic effect of cytokine storm in COVID-19 patients, this study examined the effect of Redcurrant ( Ribes rubrum ) fruit powder capsules on inflammatory cytokines of IL-6 and TNFα as primary objectives. Moreover, its effect on the COVID-19 patients’ recovery symptoms was evaluated. Methods We analyzed the clinical effect on recovery symptoms, hematological parameters, and the serum levels of interlucin-6 and TNFα in the placebo-controlled and treated patients with Redcurrant fruit powder. Results Redcurrant fruit powder capsules significantly decreased pro-inflammatory cytokines of IL-6 and TNF-α, and reduced the clinical recovery time of COVID-19 and fatigue (from 7.3 ± 2.09 to 2.9 ± 1.28 days) as well as cough (from 5.67 ± 2.4 to 2.4 ± 1.7) days compared to the control group. Conclusion Redcurrant fruit powder might be a promising herbal treatment of COVID-19, and since no considerable side effect is observed in short-term usage, it might be beneficial to start treatment as early as possible in suspected cases of COVID-19.