E-Test: An Alternative Method for Susceptibility Testing of Mycobacterium tuberculosis

Articles > Article · 2005

Authors: Selda AKÇALI, Candan ÇİÇEK, S SURUCUOGLU, B OZBAKKALOGLU

Medical Principles and Practice, Journal Indexed in SCI Expanded, International, WoS, 2005, vol 14, pp 264-267

DOI: 10.1159/000085747

Summary

OBJECTIVE: The purpose of this study was to compare the agar proportion method with the E-test method for susceptibility testing of Mycobacterium tuberculosis. MATERIALS AND METHODS: A total of 100 isolates were tested for isoniazid, rifampin, streptomycin and ethambutol susceptibility using an indirect-proportion method as well as the E-test method. RESULTS: Categorical agreement between the methods was 100% for isoniazid, rifampin, streptomycin, and ethambutol. CONCLUSION: The E-test method appears to be an alternative method to agar proportion for testing the susceptibility of M. tuberculosis isolates to the first-line antituberculous agents.

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