The effect of changes in quality of life in patients with lung cancer in the observation period (European Organization for Research and treatment of Cancer) EORTC QLQ-C 30 results of the evaluation and follow-up (AKAYAK-1 project)
Makaleler > Tam Makale · 2013
Yazarlar: Ayşen Öz, Pınar Çelik, Tuncay GÖKSEL, Ahmet Emin Erbaycu, Erhan Eser, Burcu Başarık, Kader Kıyar Gürsul, Ebru Çakır Ediz, Osman Nuri Hatipoğlu, Bedriye Atay Yayla, Sevin Başer, Hakan Baydur
European Respiratory Journal, Uluslararası, Wos, 2013, cilt 42, ss 4500-
Özet
Aim: We aimed to assess the quality of life in lung cancer patients, the effect of changes in the observation period with the results of the EORTC-C30 scale and follow-up evaluation determine the relationship between patient and cancer response. Materials and Methods: Turkish Thoracic Society, Lung - pleural Malignancies Study Group and Association of Health and Quality of Life carried out jointly Lung Cancer Quality of Life Quality of Life Project (Akayak-1) in the framework of a prospective cohort study. Stage IIIB-IV patients with primary lung cancer were monitored. Analysis of the effect of changes in quality of life STATA 12.0. Findings: Total 224 patients, mean age 61.4, the most frequently squamous cell carcinoma, adenocarcinoma was the most common in women. Average survival time was 444.9 days. Age, gender, type, stage of tumor was not significantly associated with survival. Increase of ECOG one step risk of death increased 2.3 times. Deterioration in the quality of life was found to be independent prognostic factor. Deterioration in general well-being, physical, emotional, clutch function impairment, fatigue, nausea, vomiting, pain, dyspnea, insomnia, loss of appetite, constipation, negative impact on survival. Increase in financial difficulties had negative impact on the survival. Only the social function, diarrhea were not associated with survival. Conclusion: In this study, performance status, quality of life was independent, strong prognostic factors for survival. Life time improving quality of life for these patients is extremely important.