Chemical Composition and Enzyme Inhibitory Activities of Turkish Pancratium maritimum Bulbs
Makaleler > Tam Makale · 2019
Yazarlar: Buket BOZKURT, Gülen İrem KAYA, Nehir SOMER
Natural Product Communications, SCI Expanded İndekslerine Giren Dergi, Uluslararası, Wos, 2019, cilt 14
Özet
The chemical composition of the bulbs of Pancratium maritimum L. (Amaryllidaceae) from Turkey (Pamucak, Aydın) has been determined by gas chromatography-mass spectrometry. A total of 29 compounds belonging to different skeletal types of Amaryllidaceae alkaloids were identified. Lycorine, galanthamine, crinine, and pancracine were found as major constituents. Interestingly, indole alkaloids (1-acetyl-β -carboline and galanthindole) were also detected. Acetylcholinesterase, butyrylcholinesterase, and prolyl oligopeptidase inhibitory activity potentials of the alkaloidal extract were also determined. The results of the present study show that Turkish P. maritimum comprises a rich repository for bioactive alkaloids with intriguing structural diversities.