By reducing production of vascular endothelial growth factor octreotide improves the peritoneal vascular alterations induced by hypertonic peritoneal dialysis solution
Articles > Article · 2002
Authors: ALTUĞ GÜNAL, H CELIKER, N AKPOLAT, B USTUNDAG, Soner DUMAN, F AKCİCEK
PERITONEAL DIALYSIS INTERNATIONAL, Journal Indexed in SCI Expanded, International, 2002, vol 22, pp 301-306
Summary
Objective: Chronic peritoneal dialysis (PD) may eventually result in vascular alterations of varying degree, which lead to progressive reduction in dialytic efficacy. Although the pathogenesis has not been elucidated yet, vascular endothelial growth factor (VEGF) has been proposed to play a central role in the process leading to vascular alterations.