By reducing production of vascular endothelial growth factor octreotide improves the peritoneal vascular alterations induced by hypertonic peritoneal dialysis solution
Makaleler > Tam Makale · 2002
Yazarlar: ALTUĞ GÜNAL, H CELIKER, N AKPOLAT, B USTUNDAG, Soner DUMAN, F AKCİCEK
PERITONEAL DIALYSIS INTERNATIONAL, SCI Expanded İndekslerine Giren Dergi, Uluslararası, 2002, cilt 22, ss 301-306
Özet
Objective: Chronic peritoneal dialysis (PD) may eventually result in vascular alterations of varying degree, which lead to progressive reduction in dialytic efficacy. Although the pathogenesis has not been elucidated yet, vascular endothelial growth factor (VEGF) has been proposed to play a central role in the process leading to vascular alterations.