Retrospective Evaluation of COVID-19 Infection and COVID-19 Vaccines in Heart Transplant Patients
Makaleler > Tam Makale · 2023
Yazarlar: Ümit KAHRAMAN, DENİZ AKYOL, Candan ÇİÇEK, ÖZLEM BALCIOĞLU, Çağatay ENGİN, Tahir YAĞDI, Meltem TAŞBAKAN, Mustafa ÖZBARAN
Transplantation Proceedings, SCI Expanded İndekslerine Giren Dergi, Uluslararası, Wos, 2023, cilt 55, ss 1283-1288
DOI: 10.1016/j.transproceed.2023.04.033
Özet
<p>ABSTRACTBackground.PatientswhohaveperformedsolidorgantransplantationintermsofCOVID-19infectionareincludedinthehigh-riskgroup.Inthisstudy,itwasaimedtoevaluatetherelation-shipbetweenvaccinationandretrospectiveevaluationof32patientswhounderwentahearttransplantintheclinicandtestedpositiveforSARS-CoV-2polymerasechainreaction.Methods.Inthisstudy,demographiccharacteristicsofthecases,comorbidities,timingofhearttransplantation,immunosuppressivetreatments,symptomsofCOVID-19infection,lungimagingfindings,follow-up(outpatient/inpatient),treatments,1-monthmortality,andvaccina-tionhistoriesagainstCOVID-19infectionwereevaluated.ThedataobtainedfromthestudywereanalyzedwithSPSSversion25.0.Results.The3mostcommonsymptomsarecough(37.5%),myalgia(28.1%),andfever(21.8%).COVID-19infectionwasseverein6.2%ofthepatients,moderatein37.5%,andmildin56.2%.Hospitalizationwasrequiredin5patients(15.6%,1intheintensivecareunit),andtheotherpatientswerefollowedupasanoutpatient.SevereCOVID-19infectionwasseenmorein33%ofunvaccinatedpatients;93.5%werevaccinated.Nineteenpatients(68%)werevaccinatedbeforeCOVID-19infection.OurpatientsreceivedtheCoronoVac(Sinovac,China)vaccine.Conclusion.COVID-19infectionismorelikelytobesevereandmortalinpatientswithhearttransplantrecipients.Itisalsocrucialtocomplywithpreventivemeasuresotherthanimmuniza-tioninthisgroupofpatients.ThisstudyisthelargestseriesinvestigatingCOVID-19infectioninhearttransplantrecipientpatientsinourcountry.</p>