2-DICHLOROMETHYL-1,3-DIOXOLAN-2-YL ORTHOESTERS. A POTENTIAL PROTECTING GROUP FOR SUGAR DERIVATIVES
Makaleler > Tam Makale · 2002
Yazarlar: H. Özgener, L. Yüceer
Journal of Carbohydrate Chemistry, Uluslararası, Wos, 2002, cilt 21, ss 559-567
Özet
Reactions of 2-dichloromethylene-1,3-dioxolane (2) with acetal protected sugar derivatives in neutral media gave 2-dichloromethyl-1,3-dioxolan-2-yl orthoesters. These orthoesters are readily hydrolysed under mild acidic conditions offering a new method for the preparation of readily removable protecting groups. This strategy was realised in the preparation of 6-O-acetyl-3,5-di-O-methyl-1,2-O-isopropylidene-α-d-glucofuranose.